Trifluoroacetic acid → 4-(Carboxymethyloxy)-4'-cyano-biphenyl

HRID 1598395

반응식

HRID 1598395 반응식
C([O:5][C:6]([CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH:21]=[CH:20][C:19]([C:22]#[N:23])=[CH:18][CH:17]=2)=[CH:12][CH:11]=1)=[O:7])(C)(C)C.FC(F)(F)C(O)=O>C(Cl)Cl>[C:6]([CH2:8][O:9][C:10]1[CH:11]=[CH:12][C:13]([C:16]2[CH:21]=[CH:20][C:19]([C:22]#[N:23])=[CH:18][CH:17]=2)=[CH:14][CH:15]=1)([OH:7])=[O:5]

참가 물질

4

반응물 2

HCID 6422Trifluoroacetic acidHCID 640094Tert-butyl [(4'-cyanobiphenyl-4-yl)oxy]acetate

생성물 1

HCID 432431004-(Carboxymethyloxy)-4'-cyano-biphenyl

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

32.9 g of 4-(tert.butyloxycarbonylmethyloxy)-4'-cyano-biphenyl dissolved in 250 ml of methylene chloride is mixed slowly with 137 ml of trifluoroacetic acid. After stirring for 3 hours, the reaction mixture is evaporated to dryness and the solid residue is triturated with water.

후처리

  1. customthe reaction mixture is evaporated to dryness
  2. customthe solid residue is triturated with water

출처 및 근거

ORD 기록
ord-1eb3d61987aa4b5a89fe81711f8f2f14
출처 데이터셋
uspto-grants-1998_04
특허 번호
US05736559

연결된 노트

불러오는 중…