Triethylamine → HCID 15308000, 화합물

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[CH:1]1[C:10]2[C:9]3C[CH2:12][CH:13]=[CH:14][C:8]=3N=CCC=2[S:3][CH:2]=1.[CH3:15][C:16]1[CH:33]=[CH:32][CH:31]=[CH:30][C:17]=1[C:18]([NH:20][C:21]1[CH:29]=[CH:28][C:24]([C:25](Cl)=[O:26])=[CH:23][CH:22]=1)=[O:19].C([N:36]([CH2:39][CH3:40])[CH2:37][CH3:38])C>C(Cl)Cl>[S:3]1[C:40]2[CH2:39][N:36]([C:25]([C:24]3[CH:28]=[CH:29][C:21]([NH:20][C:18](=[O:19])[C:17]4[CH:30]=[CH:31][CH:32]=[CH:33][C:16]=4[CH3:15])=[CH:22][CH:23]=3)=[O:26])[C:37]3[CH:38]=[CH:12][CH:13]=[CH:14][C:8]=3[CH2:9][C:10]=2[CH:1]=[CH:2]1

참가 물질

실험 절차

A mixture of 400 mg of 9,10-dihydro-4H-thieno[2,3-d][1]benzazepine and 600 mg of 4-[(2-methylbenzoyl)amino]benzoyl chloride is stirred in 30 ml of methylene chloride in the presence of 3 ml of triethylamine for 8 hours. The volatiles are removed in vacuo to give a residue which is partitioned between water and chloroform. The organic layer is dried (Na2 SO4) and the filtrate evaporated in vacuo to give a residue which is purified by column chromatography on silica gel by elution with 30% ethyl acetate-hexane to give 518 mg of the desired product. M+1=439.