Aluminium lithium hydride → 1H-Pyrrolo[2,3-b]pyridine-1-ethanol
반응식
[N:1]1([CH2:10][C:11](OC)=[O:12])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][N:8]=2)[CH:3]=[CH:2]1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>O1CCCC1>[N:1]1([CH2:10][CH2:11][OH:12])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][N:8]=2)[CH:3]=[CH:2]1참가 물질
4
실험 절차
A procedure similar to that described in Preparation 2 was repeated, except that 7.50 g of methyl 7-azaindol-1-acetate (prepared as described in Preparation 17), 1.80 g of lithium aluminum hydride and 260 ml of anhydrous tetrahydrofuran were used, to give 5.57 g of the title compound, melting at 52.7°-53.3° C.
후처리
- customA procedure similar to that described in Preparation 2
출처 및 근거
- ORD 기록
- ord-b173356f7db74492bbd74b2c1027be9e
- 출처 데이터셋
- uspto-grants-1998_04
- 특허 번호
- US05739345
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