Isopropanol → 3,5-Di(2,3-epoxypropoxy)-1-hydroxyxanthone

HRID 1599482

반응식

HRID 1599482 반응식
[OH-].[K+].[CH3:3][CH:4]([OH:6])[CH3:5].[OH:7][C:8]1[C:21]2[C:20](=[O:22])[C:19]3[C:14](=[C:15]([OH:23])[CH:16]=[CH:17][CH:18]=3)[O:13][C:12]=2[CH:11]=[C:10]([OH:24])[CH:9]=1.[CH2:25]([CH:27]1[O:29][CH2:28]1)Cl>O.CO>[O:6]1[CH2:5][CH:4]1[CH2:3][O:24][C:10]1[CH:9]=[C:8]([OH:7])[C:21]2[C:20](=[O:22])[C:19]3[C:14]([O:13][C:12]=2[CH:11]=1)=[C:15]([O:23][CH2:25][CH:27]1[O:29][CH2:28]1)[CH:16]=[CH:17][CH:18]=3

참가 물질

7

반응물 4

HCID 3776IsopropanolHCID 7835EpichlorohydrinHCID 14797Potassium HydroxideHCID 52816631,3,5-Trihydroxyxanthone

생성물 1

HCID 100438063,5-Di(2,3-epoxypropoxy)-1-hydroxyxanthone

시약·촉매·용매 2

HCID 887Methanol용매HCID 962Water용매

실험 절차

To a solution of 0.28 g (5.0 m mol) of potassium hydroxide in 3 ml of water was added 25 ml of 2-propanol and the 1.3 g (5.33 m mol) of 1,3,5-trihydroxyxanthone. To the above mixture was the added 7.5 ml (93.47 m mol) of epichlorohydrin, and the mixture was treated as example 4 to yield a pale yellow powder (MeOH) (21), 0.45 g (1.26 mmol, 35%)

후처리

  1. additionthe mixture was treated as example 4

출처 및 근거

ORD 기록
ord-8fe38361af8e4f57a069c7fb43572b1d
출처 데이터셋
uspto-grants-1998_04
특허 번호
US05741813

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