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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1600689생성일: 2026년 10월 26일

5-(Piperazin-1-yl)benzofuran-2-carboxamide → Vilazodone

https://huagongshe.com/reaction/1600689

반응식

참여 물질

역할이름HCID투입량
반응물5-(Piperazin-1-yl)benzofuran-2-carboxamideHCID 9834719—
반응물3-(4-Chlorobutyl)-5-cyanoindoleHCID 9881123—
생성물VilazodoneHCID 6918314—

반응 단계

5-(1-piperazinyl)benzofuran-2-carboxamide or a corresponding salt is reacted with 3-(4-chlorobutyl)-5-cyanoindole to give 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoylbenzofuran-5-yl)piperazine and optionally then converted into its acid addition salt.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05977112
출처 데이터셋uspto-grants-1999_11
ORD IDord-a4b36d73ae5647198f1d95cbd55f4e83
출처 메모uspto-grants-1999_11