Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-6-methyl-3-nitropyridine → 6-Methylpyridine-2,3-diamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-6-methyl-3-nitropyridine | HCID 226028 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 6-Methylpyridine-2,3-diamine | HCID 2734420 | 111.7% |
반응 단계
2-Amino-6-methyl-3-nitropyridine (754 mg, 4.92 mmol) was suspended in MeOH, and 10% Pd/C was added. The mixture was stirred briskly at RT under H2 (balloon). After 4 h, the reaction was filtered through Celite®, and the filtrate was concentrated under vacuum to afford the title compound (677 mg, quantitative): 1H NMR (250 MHz, CD3OD) δ 6.82 (d, 1H), 6.36 (d, 1H), 2.25 (s, 3H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05977101 |
| 출처 데이터셋 | uspto-grants-1999_11 |
| ORD ID | ord-ad8f0c7299894dfb99ddfd3081cba88d |
| 출처 메모 | uspto-grants-1999_11 |