Hydrogen iodide → HCID 19610257, 화합물
반응식
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH:8]([C:14]([O:16][CH3:17])=[O:15])[NH:9][CH:10]2[CH3:13])=[CH:5][CH:4]=1.[IH:18]>CO>[IH:18].[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH:8]([C:14]([O:16][CH3:17])=[O:15])[NH:9][CH:10]2[CH3:13])=[CH:5][CH:4]=1참가 물질
4
실험 절차
To a solution of 1,2,3,4-tetrahydro-7-methoxy-3-methoxycarbonyl-1-methyl-isoquinoline (0.526 g, 2.24 mmol) in methanol (10 mL) cooled to 0° C. was added dropwise a solution of 57% HI solution (0.33 mL). The ice bath was removed and the solution was stirred at rt for 20 min. To the bright orange solution was added ether (100 mL) and the mixture was stirred for 10 min. The light yellow precipitate was filtered and dried in vacuo (P2O5) to give the desired salt (0.736 g).
후처리
- customThe ice bath was removed
- additionTo the bright orange solution was added ether (100 mL)
- stirringthe mixture was stirred for 10 min
- filtrationThe light yellow precipitate was filtered
- dry with materialdried in vacuo (P2O5)
출처 및 근거
- ORD 기록
- ord-1cd2963fbf374d3ea3ee276fbd69043d
- 출처 데이터셋
- uspto-grants-1999_11
- 특허 번호
- US05981521
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