2,3-Dihydro-2,2-dimethyl-4-benzofurancarboxylic acid → HCID 18787456, 화합물

HRID 1602450노트

반응식

HRID 1602450 반응식
[CH3:1][C:2]1([CH3:14])[CH2:6][C:5]2=[C:7]([C:11](O)=[O:12])[CH:8]=[CH:9][CH:10]=[C:4]2[O:3]1.[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[CH3:1][C:2]1([CH3:14])[CH2:6][C:5]2=[C:7]([CH2:11][OH:12])[CH:8]=[CH:9][CH:10]=[C:4]2[O:3]1

참가 물질

3

반응물 2

HCID 148382332,3-Dihydro-2,2-dimethyl-4-benzofurancarboxylic acidHCID 21226445Aluminium lithium hydride

생성물 1

HCID 18787456HCID 18787456, 화합물수율 93%

실험 절차

2,2-Dimethyl-2,3-dihydro-benzofuran-4-carboxylic acid (8.6 g, 45 mmol) was reduced with LAH (3.41 g, 89 mmol) similar to the above procedures to give the product as a clear oil (7.35 g, 93%).

출처 및 근거

ORD 기록
ord-f588232c7a864b69a4a67b439a628439
출처 데이터셋
uspto-grants-1999_11
특허 번호
US05981571

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