4-Methyl-2-Pentanol → HCID 54535148, 화합물

반응식

[CH3:1][CH:2]([CH3:7])[CH2:3][CH:4]([OH:6])[CH3:5].[C:8](Cl)(=[O:12])[C:9]([Cl:11])=[O:10]>>[C:9]([Cl:11])(=[O:10])[C:8]([O:6][CH:4]([CH2:3][CH:2]([CH3:7])[CH3:1])[CH3:5])=[O:12]

참가 물질

반응물 2

HCID 79104-Methyl-2-Pentanol

HCID 65578Oxalyl chloride2회

생성물 1

HCID 54535148HCID 54535148, 화합물수율 88.2%

실험 절차

In this example the product was prepared in two synthetic steps. In the first step 4-methyl-2-pentanol was reacted with 50% molar excess of oxalyl chloride. Upon completion of the reaction the excess oxalyl chloride was stripped from the product at reduced pressure to produce 4-methyl-2-pentyl chlorooxalate having an assay of 96.2% and in a corrected yield of 88.2%. In the second step 4-methyl-2-pentyl chlorooxalate was reacted with 3-hydroxy-1,1-dimethylbutyl hydroperoxide in the presence of pyridine to yield the product as described below:

출처 및 근거

ORD 기록: ord-30253df839914b72b1e82d3f41c3da2c
출처 데이터셋: uspto-grants-1999_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05981787

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