N,N-dimethyl-2-nitrobenzamide → 2-Amino-N,N-dimethylbenzamide
반응식
[CH3:1][N:2]([CH3:14])[C:3](=[O:13])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[N+:10]([O-])=O>[Pd].CO>[CH3:1][N:2]([CH3:14])[C:3](=[O:13])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH2:10]참가 물질
4
실험 절차
Palladium on charcoal (0.54 g, 10% Pd by weight) was added to a solution of 2.1 g N,N-dimethyl-2-nitrobenzamide in 150 mL methanol. The resulting suspension was hydrogenated at room temperature at atmospheric pressure for three hours. After filtration of the catalyst, the solvent was removed in vacuo affording N,N-dimethyl-2-aminobenzamide (1.8 g).
후처리
- filtrationAfter filtration of the catalyst
- customthe solvent was removed in vacuo
출처 및 근거
- ORD 기록
- ord-22b2c6b43ef84da4aab3379d9e193b3c
- 출처 데이터셋
- uspto-grants-1999_11
- 특허 번호
- US05985837
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