Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Glycolide → Lactic acid glycolic acid epsilon-caprolactone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Glycolide | HCID 65432 | — |
| 반응물 | Lactide, L- | HCID 107983 | — |
| 촉매 | epsilon-CAPROLACTONE | HCID 10401 | — |
| 촉매 | Tetrakis(octanoate);tin(4+) | HCID 9961620 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | Lactic acid glycolic acid epsilon-caprolactone | HCID 69492331 | — |
반응 단계
A reactor equipped with an exhaust vent and a thermometer was charged with 263 g of L-lactide (reagent, supplied by SIGMA-ALDRICH JAPAN K.K.), 42 g of glycollide (prepared under the same conditions as those in Example 1), 194 g of ε-caprolactone (reagent, supplied by TOKYO CHEMICAL INDUSTRY CO., LTD.) and 0.01 g of tin octanoate (reagent, supplied by SIGMA-ALDRICH JAPAN K.K.) as a catalyst, and the pressure inside the reactor was reduced to 1×10−3 mmHg with a vacuum pump, followed by polymerization at 190° C. for 24 hours. After the reaction, a copolymer was dissolved in chloroform and purified by precipitation in methanol, to give a lactic acid/glycolic acid/ε-caprolactone copolymer.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07736393B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-0d1d811887594b48876707271c6f6132 |
| 출처 메모 | uspto-grants-2010_06 |