Oxalyl chloride → 16-Hexadecanoyloxyhexadecanoyl chloride

HRID 1603973노트

반응식

HRID 1603973 반응식
[C:1]([O:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][C:34]([OH:36])=O)(=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].C(Cl)(=O)C([Cl:40])=O>O1CCCC1>[C:1]([O:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][C:34]([Cl:40])=[O:36])(=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

참가 물질

4

반응물 2

HCID 65578Oxalyl chlorideHCID 1960674616-Hexadecanoyloxyhexadecanoic acid

생성물 1

HCID 2171198416-Hexadecanoyloxyhexadecanoyl chloride수율 100%

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

16-Hexadecanoyloxyhexadecanoic acid (7.73 g, 15.13 mmol) prepared as in (c) above was dissolved in tetrahydrofuran (140 ml) and oxalyl chloride (4.80 g, 37.83 mmol) was added dropwise. The mixture was stirred at room temperature for 3 days and then the solvent and unreacted oxalyl chloride were evaporated under reduced pressure to give 8.0 g (100%) of the title compound.

후처리

  1. customthe solvent and unreacted oxalyl chloride were evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-9fc4cc17c55d41b1a521b374511dd0e5
출처 데이터셋
uspto-grants-1999_11
특허 번호
US05990263

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