Ethyl acetamidoacetate → HCID 21548855, 화합물

HRID 1605035노트

반응식

HRID 1605035 반응식
[C:1]([NH:4][CH2:5][C:6]([O:8]CC)=O)(=[O:3])[CH3:2].[CH2:11]([NH2:33])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32]>C(OCC)(=O)C>[CH2:11]([NH:33][C:6](=[O:8])[CH2:5][NH:4][C:1](=[O:3])[CH3:2])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32]

참가 물질

4

반응물 2

HCID 74702Ethyl acetamidoacetateHCID 842181-Docosanamine

생성물 1

HCID 21548855HCID 21548855, 화합물

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

반응 조건

온도
150 °C

실험 절차

A mixture consisting of 1.13 gm (0.01 mol) of ethyl N-acetyl-glycinate and 2.50 gm (0.0078 mol) of n-docosyl-amine was heated for 90 minutes at 150°C., while stirring. Thereafter, ethyl acetate was added to the hot reaction mixture, and upon cooling of the mixture a crystalline substance separated out which was collected and again recrystallized from ethyl acetate in the presence of activated charcoal and silicagel. 1.5 gm (55% of theory) of the compound of the formula ##EQU6## having a melting point of 135°-137°C. were obtained.

후처리

  1. temperatureupon cooling of the mixture a crystalline substance
  2. customseparated out which
  3. customwas collected
  4. customagain recrystallized from ethyl acetate in the presence of activated charcoal and silicagel
  5. customwere obtained

출처 및 근거

ORD 기록
ord-e1d3dc7ec3ff455d899ee8587f13e8b2
출처 데이터셋
uspto-grants-1976_04
특허 번호
US03948943

반응 노트

불러오는 중…