Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → Ipriflavone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | Morpholine | HCID 8083 | — |
| 반응물 | Ethylorthoformate | HCID 53630039 | — |
| 반응물 | 2-Hydroxy-4-isopropyloxy-phenyl-benzyl ketone | HCID 54277918 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Ipriflavone | HCID 3747 | — |
반응 단계
27 g of 2-hydroxy-4-isopropyloxy-phenyl-benzyl ketone, 22 g of ethyl orthoformate and 5 g of morpholine are boiled for 8 hours in 200 ml of dimethyl formamide. The ethanol formed during the reaction is removed through a fraction head. Then the major part of solvent is distilled off in vacuum and the residue is diluted with dilute aqueous hydrochloric acid. The crude product is filtered and recrystallized from acetone, yielding 24 g of 7-isopropyloxy-isoflavone of m.p. 115°-117°C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03949085 |
| 출처 데이터셋 | uspto-grants-1976_04 |
| ORD ID | ord-9195dddb56f746f8a95ceb80bded6348 |
| 출처 메모 | uspto-grants-1976_04 |