Water → Ipriflavone

HRID 1605175

반응식

HRID 1605175 반응식
[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:18])[C:7]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)=[CH:8][O:9]2)=[CH:4][CH:3]=1.C(=O)([O-])[O-].[K+].[K+].[CH:25](Br)([CH3:27])[CH3:26].O>CN(C)C=O>[CH:25]([O:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:18])[C:7]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)=[CH:8][O:9]2)=[CH:4][CH:3]=1)([CH3:27])[CH3:26]

참가 물질

6

반응물 4

HCID 962WaterHCID 63582-BromopropaneHCID 11430Potassium CarbonateHCID 53768917-Hydroxyisoflavone

생성물 1

HCID 3747Ipriflavone

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

12 g of 7-hydroxy-isoflavone are boiled for 2 hours under a reflux condenser with 10 g of potassium carbonate and 9 g of isopropyl bromide in 40 ml of dimethyl formamide. On pouring the reaction mixture into water, the separated product is recrystallized from acetone, yielding 7-isopropoxy-isoflavone. In a similar way all the other isoflavone derivatives described in Example 7 can be prepared.

후처리

  1. customthe separated product is recrystallized from acetone

출처 및 근거

ORD 기록
ord-2b150183f52844d682b962b62bb5ae35
출처 데이터셋
uspto-grants-1976_04
특허 번호
US03949085

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