Aldoxime → Acetonitrile oxide

HRID 1606003노트

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HRID 1606003 반응식
ClCl.[CH:3](=[N:5][OH:6])[CH3:4].C(=O)(O)[O-].[Na+].[Cl:12][C:13]1[C:14](=[O:21])[CH:15]=[CH:16][C:17](=[O:20])[C:18]=1[Cl:19]>O>[C:3](#[N+:5][O-:6])[CH3:4].[Cl:12][C:13]1[C:14](=[O:21])[C:15]2[C:3]([CH3:4])=[N:5][O:6][C:16]=2[C:17](=[O:20])[C:18]=1[Cl:19]

참가 물질

7

반응물 4

HCID 7863AldoximeHCID 24526ChlorineHCID 1384232,3-Dichloro-1,4-benzoquinoneHCID 516892Sodium Bicarbonate

생성물 2

HCID 522391Acetonitrile oxideHCID 21545721HCID 21545721, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A solution of acetonitrile oxide was prepared by passing chlorine (10.8 grams) over 30 minutes into a stirred suspension of acetaldoxime (9 grams) and sodium bicarbonate (25.2 grams) in water at 0° C was added 2,3-dichlorobenzoquinone (17.7 grams) portionwise over 15 minutes. The mixture was stirred at 0°-5° C for 2 hours and then extracted with methylene chloride. The dried extracts were evaporated to dryness under reduced pressure and the residue recrystallized from ethanol to give the desired product as yellow crystals having a melting point of 214°-215° C.

후처리

  1. customover 30 minutes
  2. extractionextracted with methylene chloride
  3. customThe dried extracts were evaporated to dryness under reduced pressure
  4. customthe residue recrystallized from ethanol

출처 및 근거

ORD 기록
ord-a707d3f725624214a4ace320b4d506a7
출처 데이터셋
uspto-grants-1976_04
특허 번호
US03952003

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