HCID 12397258, 화합물 → HCID 54332840, 화합물

HRID 1606311노트

반응식

HRID 1606311 반응식
[CH2:1]([O:8]C1C=CC(C=O)=NC=1CS(C)(=O)=O)C1C=CC=CC=1.C1OC2C=CC(C([N+]#[C-])(C)C)=CC=2O1.[OH:36][C:37]1[CH:38]=[CH:39][C:40]([CH:48]([CH2:50][NH:51][CH:52]([CH3:61])[CH2:53][C:54]2[CH:59]=[CH:58][C:57]([OH:60])=[CH:56][CH:55]=2)[OH:49])=[N:41][C:42]=1[CH2:43][S:44]([CH3:47])(=[O:46])=[O:45]>>[OH:36][C:37]1[CH:38]=[CH:39][C:40]([CH:48]([CH2:50][NH:51][CH:52]([CH3:61])[CH2:53][C:54]2[CH:55]=[CH:56][C:57]3[O:60][CH2:1][O:8][C:58]=3[CH:59]=2)[OH:49])=[N:41][C:42]=1[CH2:43][S:44]([CH3:47])(=[O:46])=[O:45]

참가 물질

4

반응물 3

HCID 12397258HCID 12397258, 화합물HCID 21546381HCID 21546381, 화합물HCID 21546387HCID 21546387, 화합물

생성물 1

HCID 54332840HCID 54332840, 화합물

실험 절차

Reacting 5-benzyloxy-6-methanesulfonylmethyl-2-pyridinecarboxaldehyde with 3,4-methylenedioxyphenylisopropyl isocyanide followed by reduction of the intermediate amide and hydrogenation of the amine gives 5-hydroxy-6-methanesulfonylmethyl-α-[2-(3,4-methylenedioxyphenyl)-1-methylethylaminomethyl]-2-pyridinemethanol.

출처 및 근거

ORD 기록
ord-9a81e8849eb840599fc14ceb295f5fbe
출처 데이터셋
uspto-grants-1976_04
특허 번호
US03952101

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