Acetic Acid → HCID 13066647, 화합물

HRID 1606635노트

반응식

HRID 1606635 반응식
C([O:4][C:5]1[CH:36]=[CH:35][CH:34]=[CH:33][C:6]=1[C:7]([NH:9][C:10]1[CH:19]=[CH:18][C:17]([NH:20][C:21](=[O:32])[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=2[O:28]C(=O)C)=[CH:16][C:11]=1[C:12]([O:14][CH3:15])=[O:13])=[O:8])(=O)C.C(=O)([O-])[O-].[Na+].[Na+].C(O)(=O)C>CO.O>[C:7]([NH:9][C:10]1[CH:19]=[CH:18][C:17]([NH:20][C:21](=[O:32])[C:22]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[OH:28])=[CH:16][C:11]=1[C:12]([O:14][CH3:15])=[O:13])(=[O:8])[C:6]1[C:5](=[CH:36][CH:35]=[CH:34][CH:33]=1)[OH:4]

참가 물질

6

반응물 3

HCID 176Acetic AcidHCID 10340Sodium CarbonateHCID 13066645HCID 13066645, 화합물

생성물 1

HCID 13066647HCID 13066647, 화합물수율 86.5%

시약·촉매·용매 2

HCID 887Methanol용매HCID 962Water용매2회

실험 절차

In 150 ml methanol was dissolved 5.3 g of methyl 2,5-bis(2'-acetoxybenzamido)-benzoate obtained in Example 3. To the solution was added 2.5 g of sodium carbonate dissolved in 40 ml of water and then the mixture was stirred at room temperature for 30 minutes. The mixture was poured into 500 ml of water containing 10 ml of acetic acid to precipitate crystals. The crystals were recovered by filtration, washed with water, dried and recrystallized from ethyl acetate to yield 3.8 g of methyl 2,5-bis(salicylamido)-benzoate having a melting point between 243° - 244°C.

후처리

  1. customto precipitate crystals
  2. filtrationThe crystals were recovered by filtration
  3. washwashed with water
  4. customdried
  5. customrecrystallized from ethyl acetate

출처 및 근거

ORD 기록
ord-a47513806b9f477b85e94148d2e689d5
출처 데이터셋
uspto-grants-1976_04
특허 번호
US03953496

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