Ethylene Glycol → 2-(4-Bromophenyl)-2-methyl-1,3-dioxolane

HRID 1606710

반응식

HRID 1606710 반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:10])[CH3:9])=[CH:4][CH:3]=1.[CH2:11](O)[CH2:12][OH:13].C1(C)C=CC(S(O)(=O)=O)=CC=1.O>C1(C)C=CC=CC=1>[CH3:9][C:8]1([C:5]2[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][CH:4]=2)[O:13][CH2:12][CH2:11][O:10]1

참가 물질

6

반응물 4

HCID 174Ethylene GlycolHCID 962WaterHCID 6101p-Toluenesulfonic acidHCID 7466p-Bromoacetophenone

생성물 1

HCID 6149202-(4-Bromophenyl)-2-methyl-1,3-dioxolane

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

In 1200 milliliters of toluene in a flask equipped with a Dean-Stark tube are dissolved 100 grams of p-bromoacetophenone; and to this solution is added 140 grams of ethylene glycol and 5 grams of p-toluenesulphonic acid. This mixture is refluxed until no further water collects in the Dean-Stark tube. After distilling off 600 milliliters of toluene, the remaining solution is decanted off and evaporated to dryness in vacuo to obtain 2-methyl-2-(p-bromophenyl)-1,3-dioxolane.

후처리

  1. distillationAfter distilling off 600 milliliters of toluene
  2. customthe remaining solution is decanted off
  3. customevaporated to dryness in vacuo

출처 및 근거

ORD 기록
ord-1b11d01c2b12444d9b70226ab55fb749
출처 데이터셋
uspto-grants-1976_04
특허 번호
US03953525

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