Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenyl glycidyl ether → 1-Phenoxy-2-propanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenyl glycidyl ether | HCID 31217 | — |
| 반응물 | Benzyltrimethylammonium hydroxide | HCID 66854 | — |
| 반응물 | 2',6'-Dihydroxyacetophenone | HCID 69687 | — |
| 용매 | Glycol monoethyl ether | HCID 8076 | — |
| 생성물 | 1-Phenoxy-2-propanol | HCID 92839 | — |
반응 단계
A solution of 2,6-dihydroxyacetophenone (15.2g.), phenylglycidyl ether (15.0 g) and benzyltrimethylammonium hydroxide (5 drops of a 40% solution) in 2-ethoxyethanol (75 ml) was heated under reflux for 48 hours. The solvent was removed under reduced pressure and the resulting solid was washed with ether. Recrystallization from aqueous ethanol gave 1-(2-acetyl-3-hydroxyphenoxy(-2-hydroxy-3-phenoxypropane, 19.0 g, as pale lemon needles, m.p. 100.5°-101.5° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03953604 |
| 출처 데이터셋 | uspto-grants-1976_04 |
| ORD ID | ord-4c190907babd413c942a9bdef2d33127 |
| 출처 메모 | uspto-grants-1976_04 |