Ethanolamine → 2-(beta-Hydroxyethyl)amino-6-(beta-hydroxyethyl)amino-4-chloronitrobenzene

HRID 1606851노트

반응식

HRID 1606851 반응식
Cl[C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4](Cl)[C:3]=1[N+:10]([O-:12])=[O:11].[CH2:13]([CH2:15][NH2:16])[OH:14]>>[OH:14][CH2:13][CH2:15][NH:16][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4]([NH:16][CH2:15][CH2:13][OH:14])[C:3]=1[N+:10]([O-:12])=[O:11]

참가 물질

3

반응물 2

HCID 700EthanolamineHCID 292282,4,6-Trichloronitrobenzene

생성물 1

HCID 200710912-(beta-Hydroxyethyl)amino-6-(beta-hydroxyethyl)amino-4-chloronitrobenzene

실험 절차

0.132 mole (30 g) of 2,4,6-trichloronitrobenzene were heated at 95° C. in 120 ml of ethanolamine. After 30 minutes the reaction medium was poured over 240 g of an ice-water mixture. The desired product precipitated out and was filtered, washed with water and then dried under vacuum in the presence of phosphorus pentoxide. After recrystallization from absolute ethanol, it melted at 154° C.

후처리

  1. customThe desired product precipitated out
  2. filtrationwas filtered
  3. washwashed with water
  4. dry with materialdried under vacuum in the presence of phosphorus pentoxide
  5. customAfter recrystallization from absolute ethanol, it melted at 154° C.

출처 및 근거

ORD 기록
ord-03db87c1a2a64f06919127391a9822ca
출처 데이터셋
uspto-grants-1989_09
특허 번호
US04863482

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