Hydrate;hydrochloride → HCID 178419078, 화합물

HRID 1607315노트

반응식

HRID 1607315 반응식
Cl.O.[NH2:3][CH:4]([C:11]([OH:13])=[O:12])[CH2:5][C:6]1[N:10]=[CH:9][NH:8][CH:7]=1.Cl.O>O>[NH2:3][C@H:4]([C:11]([OH:13])=[O:12])[CH2:5][C:6]1[N:10]=[CH:9][NH:8][CH:7]=1

참가 물질

4

반응물 2

HCID 21885828Hydrate;hydrochlorideHCID 178479203HCID 178479203, 화합물

생성물 1

HCID 178419078HCID 178419078, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

HCl.H2O: D,L-His.HCl.H2O (3.2 g) and the appropriate polymer were slurried in water (5 ml) and the slurry was heated to complete dissolution. The hot solution was filtered and allowed to stand at 50° C. for 20 hrs without agitation. The crystals were collected by filtration and the enantiomeric excess was determined. The results are summarized in Table VI.

후처리

  1. temperaturethe slurry was heated
  2. dissolutiondissolution
  3. filtrationThe hot solution was filtered
  4. filtrationThe crystals were collected by filtration

출처 및 근거

ORD 기록
ord-65c5551bfb56438f89c3c7abed1f1c95
출처 데이터셋
uspto-grants-1989_09
특허 번호
US04864031

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