Ethyl benzylidenecyanoacetate → Ethyl 2-cyano-3-phenylpropanoate

HRID 1607388

반응식

HRID 1607388 반응식
[CH2:1]([O:3][C:4](=[O:15])[C:5]([C:13]#[N:14])=[CH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH3:2]>C1C=CC=CC=1.[Pd]>[CH2:1]([O:3][C:4](=[O:15])[CH:5]([C:13]#[N:14])[CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH3:2]

참가 물질

4

반응물 1

HCID 74845Ethyl benzylidenecyanoacetate

생성물 1

HCID 228103Ethyl 2-cyano-3-phenylpropanoate수율 92.5%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 241Benzene용매

실험 절차

A solution of 4.56 g of the ester obtained in 30 ml of benzene was hydrogenated over 0.45 g of a 10% palladium/charcoal under a hydrogen atmosphere at room temperature for 4 hours. After filtration of the catalyst, the reaction mixture was concentrated under reduced pressure to obtain 4.26 g of 2-cyano-3-phenylpropionic acid ethyl ester as a colorless oil.

후처리

  1. filtrationAfter filtration of the catalyst
  2. concentrationthe reaction mixture was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-c3f8c538c3994304819a7c2b309f2c97
출처 데이터셋
uspto-grants-1989_09
특허 번호
US04863904

연결된 노트

불러오는 중…