Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Morpholine → 4-[(4-Bromo-2,5-difluorophenyl)sulfonyl]-morpholine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Morpholine | HCID 8083 | — |
| 반응물 | 4-Bromo-2,5-difluorobenzenesulfonyl Chloride | HCID 574590 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-[(4-Bromo-2,5-difluorophenyl)sulfonyl]-morpholine | HCID 68606358 | — |
반응 단계
Morpholine (0.16 ml) was added to a stirred solution of 4-bromo-2,5-difluoro-benzenesulfonyl chloride (0.18 g) in dichloromethane (6 ml) under nitrogen. The reaction mixture was stirred overnight and then quenched with water. The organic phase was dried (MgSO4) and concentrated in vacuo to give the sub-title compound as a white solid (200 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07737135B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-39a68fdc2cf342168e2bccff054cfd0b |
| 출처 메모 | uspto-grants-2010_06 |