Acetic Acid → HCID 15085580, 화합물

HRID 1607524노트

반응식

HRID 1607524 반응식
[CH3:1][NH:2][C:3](=[O:14])[NH:4][C:5]1[CH:9]=[CH:8][S:7][C:6]=1[C:10](OC)=[O:11].CN(C)C=O.C(O)(=O)C>[OH-].[K+]>[CH3:1][N:2]1[C:10](=[O:11])[C:6]2[S:7][CH:8]=[CH:9][C:5]=2[NH:4][C:3]1=[O:14]

참가 물질

5

반응물 3

HCID 176Acetic AcidHCID 6228DimethylformamideHCID 15085579HCID 15085579, 화합물

생성물 1

HCID 15085580HCID 15085580, 화합물

시약·촉매·용매 1

HCID 14797Potassium Hydroxide용매

실험 절차

Methyl 3-(N'-methylureido)thiophene-2-carboxylate (4,2 g, 20 mmol) was suspended with stirring in 5% aqueous potassium hydroxide (50 ml). Dimethylformamide was added until a clear solution was obtained. Stirring was continued for 30 min, whereafter the solution was neutralized with acetic acid. This afforded a crystalline precipitate of the title compound, which was separated by filtration and washed with water. M.p.>300° C.

후처리

  1. customwas obtained

출처 및 근거

ORD 기록
ord-f9681ba618da4a4bbc084a425f84d94f
출처 데이터셋
uspto-grants-1989_09
특허 번호
US04866065

반응 노트

불러오는 중…