Ethyl Acetate → 3-Hydroxyacetyl-6-(benzyloxy)indole
반응식
Cl[CH2:2][C:3]([C:5]1[C:13]2[C:8](=[CH:9][C:10]([O:14][CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[CH:11][CH:12]=2)[NH:7][CH:6]=1)=[O:4].C(N)=[O:23].O.CCOC(C)=O>O1CCOCC1>[OH:23][CH2:2][C:3]([C:5]1[C:13]2[C:8](=[CH:9][C:10]([O:14][CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[CH:11][CH:12]=2)[NH:7][CH:6]=1)=[O:4]참가 물질
5
반응 조건
- 온도
- 110 °C
실험 절차
A solution of 11 in dioxane was added to formamide-water (10:1). The mixture was stirred at 110° C. for 10 hrs., then worked up and purified as described above to yield 82% of 13 as colorless prisms with mp 194°-195° C. (EtOAc).
후처리
- custompurified
출처 및 근거
- ORD 기록
- ord-e6c7b58cdebc4ee5bf79639f88691b22
- 출처 데이터셋
- uspto-grants-1989_09
- 특허 번호
- US04866084
반응 노트
불러오는 중…