1-Nitropropane → 1-Hydroxy-2-Ethylbenzimidazole-3-Oxide

HRID 1607721노트

반응식

HRID 1607721 반응식
[N+]([CH2:4][CH2:5][CH3:6])([O-])=O.[CH:7]1[CH:15]=[CH:14][C:13]2[C:9](=[N:10][O:11][N+:12]=2[O-:16])[CH:8]=1.C(NCC)C>O1CCCC1>[OH:11][N:10]1[C:9]2[CH:8]=[CH:7][CH:15]=[CH:14][C:13]=2[N+:12]([O-:16])=[C:4]1[CH2:5][CH3:6]

참가 물질

5

반응물 3

HCID 79031-NitropropaneHCID 8021DiethylamineHCID 68075Benzofuroxan

생성물 1

HCID 145490291-Hydroxy-2-Ethylbenzimidazole-3-Oxide

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

To a mixture containing 1-nitropropane (10.7 g., 0.12 moles), benzofuroxan (13.6 g., 0.10 moles) and tetrahydrofuran (50 ml.) is added dropwise diethylamine (8.7 g., 0.12 moles). The reaction temperature rises almost to reflux on addition of amine. Upon completion, the mixture is allowed to cool and then sit overnight.

후처리

  1. temperatureto cool

출처 및 근거

ORD 기록
ord-afe3635a6c0c420ca085ef8a31f0ab0a
출처 데이터셋
uspto-grants-1989_09
특허 번호
US04866175

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