2-Quinolinecarboxaldehyde → HCID 54189210, 화합물

HRID 1608176

반응식

HRID 1608176 반응식
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]=O.[C:13]1([CH3:23])[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([NH:21][NH2:22])=[O:20])[CH:14]=1>C(O)C>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]=[N:22][NH:21][C:19](=[O:20])[C:15]1[CH:16]=[CH:17][CH:18]=[C:13]([CH3:23])[CH:14]=1

참가 물질

4

반응물 2

HCID 796192-QuinolinecarboxaldehydeHCID 83082m-Toluohydrazide

생성물 1

HCID 54189210HCID 54189210, 화합물수율 36.2%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A mixture of 3.3 gm (0.021 mole) of 2-quinolinecarboxaldehyde, 3.15 gm (0.021 mole) of m-toluic acid hydrazide and 150 ml of absolute ethanol is refluzed 10 hr. The hot solution is filtered then diluted with water until cloudy. The mixture is cooled to room temperature and then chilled. The solid is collected to give 2.2 gm (36%) of the title compound having a melting point of 187.5°-188° C. after recrystallizing from methylene chloride/diethyl ether.

후처리

  1. filtrationThe hot solution is filtered
  2. additionthen diluted with water until cloudy
  3. temperaturechilled
  4. customThe solid is collected

출처 및 근거

ORD 기록
ord-7d855082c6a547da820846c7f6518b6e
출처 데이터셋
uspto-grants-1989_09
특허 번호
US04870082

연결된 노트

불러오는 중…