Boron → HCID 13527805, 화합물

HRID 1608377노트

반응식

HRID 1608377 반응식
[CH3:1][Li].[C:3]([B:7](OC(C)C)[O:8][CH:9]([CH3:11])[CH3:10])([CH3:6])([CH3:5])[CH3:4].[B]>>[C:3]([B:7]([CH3:1])[O:8][CH:9]([CH3:11])[CH3:10])([CH3:6])([CH3:5])[CH3:4]

참가 물질

4

반응물 3

HCID 5462311BoronHCID 13183022Dipropan-2-yl tert-butylboronateHCID 178418348HCID 178418348, 화합물

생성물 1

HCID 13527805HCID 13527805, 화합물

실험 절차

The reaction was run following the procedure described in Example 1 using methyllithum (38.4 mmol, 24.6 mL) and tert-butyldiisopropoxyborane (7.15 g, 38.3 mmol). Volatiles were removed at atmospheric pressure and the product distilled to yield 3.9 g (27.5 mmol, 73%), bp 90°-92° C. (741 mm Hg); proton NMR (CDCl3) δ4.30 (septet, J=18 Hz, 1H), 1.15 (d, J=18 Hz, 6H), 0.83 (s, 9H), 0.30 (brs, 3H); boron NMR (neat) δ+52.9 ppm (s).

후처리

  1. customVolatiles were removed at atmospheric pressure
  2. distillationthe product distilled
  3. customto yield 3.9 g (27.5 mmol, 73%), bp 90°-92° C. (741 mm Hg)

출처 및 근거

ORD 기록
ord-8bb8c9787134461f8d837237b50ba6ec
출처 데이터셋
uspto-grants-1989_09
특허 번호
US04870212

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