Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,4-dihydro-3H-2-benzopyran-3-one → (E)-2-[2-[3-[2-[4-(cyclobutyl)-2-thiazolyl]ethenyl]phenylamino]-2-oxoethyl]benzyl alcohol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,4-dihydro-3H-2-benzopyran-3-one | HCID 78092 | — |
| 반응물 | (E)-3-[2-[4-(cyclobutyl)-2-thiazolyl]ethenyl]benzeneamine | HCID 15136086 | — |
| 생성물 | (E)-2-[2-[3-[2-[4-(cyclobutyl)-2-thiazolyl]ethenyl]phenylamino]-2-oxoethyl]benzyl alcohol | HCID 44211474 | — |
반응 단계
A solution of 0.256 g of (E)-3-[2-[4-(cyclobutyl)-2-thiazolyl]ethenyl]benzeneamine and 0.148 g of 3-isochromanone was heated in a 126° C. oil bath for 17 hr. The residual materials were purified by silica gel chromatography using ethyl acetate-hexane (1:4 v/v) as the eluant to yield (E)-2-[2-[3-[2-[4-(cyclobutyl)-2-thiazolyl]ethenyl]phenylamino]-2-oxoethyl]benzyl alcohol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05399702 |
| 출처 데이터셋 | uspto-grants-1995_03 |
| ORD ID | ord-976394392c5548f1b9eeac037a3d1c01 |
| 출처 메모 | uspto-grants-1995_03 |