Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → Isopropyl 1-methyl-3-indoleacetimidate hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Isopropanol | HCID 3776 | — |
| 반응물 | 2-(1-methyl-1H-indol-3-yl)acetonitrile | HCID 10654720 | — |
| 생성물 | Isopropyl 1-methyl-3-indoleacetimidate hydrochloride | HCID 22907276 | 44% |
반응 단계
Hydrogen chloride was bubbled through a stirred solution of 7.5 g (44 mmol) of 1-methylindole-3-acetonitrile in 100ml of dry isopropanol at room temperature. After 4 hours, the solvent was removed under reduced pressure and the residue was triturated with diethyl ether to give 5.17 g (44%) of isopropyl 1-methyl-3-indoleacetimidate hydrochloride as a white solid of melting point 133° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05399712 |
| 출처 데이터셋 | uspto-grants-1995_03 |
| ORD ID | ord-968189737b3e40409f7af5ed50844dcc |
| 출처 메모 | uspto-grants-1995_03 |