Trifluoroacetic acid → HCID 67805215, 화합물

HRID 1609619노트

반응식

HRID 1609619 반응식
[CH2:1]([O:8][C:9]([CH:11]1[CH2:19][CH:18]2[CH:13]([CH2:14][CH2:15][CH2:16][CH2:17]2)[N:12]1[C:20](=[O:31])[C@H:21]([CH3:30])[NH:22]C(OC(C)(C)C)=O)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:32][C:33]([F:38])([F:37])[C:34]([OH:36])=[O:35]>>[F:32][C:33]([F:38])([F:37])[C:34]([OH:36])=[O:35].[CH2:1]([O:8][C:9]([CH:11]1[CH2:19][CH:18]2[CH:13]([CH2:14][CH2:15][CH2:16][CH2:17]2)[N:12]1[C:20](=[O:31])[C@H:21]([CH3:30])[NH2:22])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 6422Trifluoroacetic acidHCID 67806908HCID 67806908, 화합물

생성물 1

HCID 67805215HCID 67805215, 화합물

실험 절차

21.5 g of Boc-Ala-Oic-OBzl are dissolved in 50 ml of trifluoroacetic acid. The solution is concentrated in vacuo, and the residue is digested several times with diisopropyl ether and is dried in vacuo. Yield: 21 g. The proton signal for the tertiary-butyl group is completely absent in the NMR spectrum.

후처리

  1. concentrationThe solution is concentrated in vacuo
  2. customis dried in vacuo

출처 및 근거

ORD 기록
ord-8a009f164b1d445291641c52e51200e5
출처 데이터셋
uspto-grants-1995_03
특허 번호
US05401766

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