Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pinacol → 2-[5-Chloro-2-(phenylmethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pinacol | HCID 6425 | — |
| 반응물 | 2-Benzyloxy-5-chlorobenzeneboronic acid | HCID 4198740 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 2-[5-Chloro-2-(phenylmethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 67277773 | — |
반응 단계
Pinacol (3.24 g) was added to a solution of [5-chloro-2-(phenylmethoxy)phenyl]-boronic acid (6 g) in diethyl ether, and stirred for 24 h. 4 A molecular sieves and pinacol (1.5 g) were added, stirred for a further 24 h. The sieves were filtered and the filtrate was washed with water and brine, then dried (MgSO4) and concentrated in vacuo. Yield 6.8 g.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07737135B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-cad92530f2bb4c4bac0ae274992f4d4c |
| 출처 메모 | uspto-grants-2010_06 |