Tetrahydrofuran → Tert-butyl 4-[[5-benzylsulfanyl-7-[(1-hydroxy-4-methylpentan-2-yl)amino]-[1,3]thiazolo[4,5-d]pyrimidin-2-yl]amino]piperidine-1-carboxylate

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][c:15]2[s:16][c:17]3[c:18]([n:19][c:20]([S:24][CH2:25][c:26]4[cH:27][cH:28][cH:29][cH:30][cH:31]4)[n:21][c:22]3[Cl:23])[n:32]2)[CH2:12][CH2:13]1.[NH2:33][CH:34]([CH2:35][CH:36]([CH3:37])[CH3:38])[CH2:39][OH:40].[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][c:15]2[s:16][c:17]3[c:18]([n:19][c:20]([S:24][CH2:25][c:26]4[cH:27][cH:28][cH:29][cH:30][cH:31]4)[n:21][c:22]3[NH:33][CH:34]([CH2:35][CH:36]([CH3:37])[CH3:38])[CH2:39][OH:40])[n:32]2)[CH2:12][CH2:13]1