5-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione → 1-(Cyclobutyl)methyl-5-isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione

HRID 1611262

반응식

HRID 1611262 반응식
[CH:1]([C:4]1[C:5](=[O:20])[NH:6][C:7](=[O:19])[NH:8][C:9]=1[S:10][C:11]1[CH:16]=[C:15]([CH3:17])[CH:14]=[C:13]([CH3:18])[CH:12]=1)([CH3:3])[CH3:2].C1(C)C=CC(S(O[CH2:31][CH:32]2[CH2:35][CH2:34][CH2:33]2)(=O)=O)=CC=1>>[CH:32]1([CH2:31][N:8]2[C:9]([S:10][C:11]3[CH:12]=[C:13]([CH3:18])[CH:14]=[C:15]([CH3:17])[CH:16]=3)=[C:4]([CH:1]([CH3:3])[CH3:2])[C:5](=[O:20])[NH:6][C:7]2=[O:19])[CH2:35][CH2:34][CH2:33]1

참가 물질

3

실험 절차

5-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione and (cyclobutyl)methyl para-toluenesulfonate were reacted by the same way with the example 1 to obtain the titled compound (147 mg, yield: 41.0%).

출처 및 근거

ORD 기록
ord-9fa75aaa0402485fafc70c9260c76daf
출처 데이터셋
uspto-grants-2006_01
특허 번호
US06987114B1

연결된 노트

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