4-[2,6-Dichloro-4-(phenylmethoxy)phenoxy]butan-1-ol → 3,5-Dichloro-4-(4-hydroxybutoxy)phenol
반응식
[Cl:1][C:2]1[CH:13]=[C:12]([O:14]CC2C=CC=CC=2)[CH:11]=[C:10]([Cl:22])[C:3]=1[O:4][CH2:5][CH2:6][CH2:7][CH2:8][OH:9].[H][H]>[Pd]>[Cl:1][C:2]1[CH:13]=[C:12]([OH:14])[CH:11]=[C:10]([Cl:22])[C:3]=1[O:4][CH2:5][CH2:6][CH2:7][CH2:8][OH:9]참가 물질
4
실험 절차
This compound was prepared in a manner analogous to that of Step A of this example, using 12.2 grams (0.036 mole) of 4-[2,6-dichloro-4-(phenylmethoxy)phenoxy]butan-1-ol and 0.5 gram (catalyst) of 10% palladium on carbon and a theoretical amount of hydrogen gas in a Parr Hydrogenator. The yield of the subject compound was 9.3 grams. The NMR spectrum was consistent with the proposed structure.
후처리
- customThis compound was prepared in a manner analogous to that of Step A of this example
출처 및 근거
- ORD 기록
- ord-68940b919345426ba63d0c73b4754ffe
- 출처 데이터셋
- uspto-grants-2006_01
- 특허 번호
- US06987194B2
반응 노트
불러오는 중…