4,5,6,7-Tetrahydro-1-benzofuran-4-one → 5-methyl-6,7-dihydrobenzofuran-4(5H)-one

HRID 1612159

반응식

HRID 1612159 반응식
[CH3:1][CH:2]1[C:10](=[O:11])[C:6]2[CH:7]=[CH:8]S[C:5]=2[CH2:4][CH2:3]1.[O:12]1C2CCCC(=O)C=2C=C1>>[CH3:1][CH:2]1[C:10](=[O:11])[C:6]2[CH:7]=[CH:8][O:12][C:5]=2[CH2:4][CH2:3]1

참가 물질

3

반응물 2

HCID 27335414,5,6,7-Tetrahydro-1-benzofuran-4-oneHCID 154115085-methyl-6,7-dihydro-1-benzothiophen-4(5H)-one

생성물 1

HCID 138176905-methyl-6,7-dihydrobenzofuran-4(5H)-one

실험 절차

Following the procedure for the preparation of 5-methyl-6,7-dihydro-1-benzothiophen-4(5H)-one but substituting 6,7-dihydro-1-benzofuran-4(5H)-one and making non-critical variations provided the title compound as a oil: 1H NMR (CDCl3) δ 1.24, 1.95, 2.25, 2.55, 2.93, 6.68, 7.33; MS (EI) m/z (rel. intensity) 150 (M+, 54), 150 (54), 121 (10), 109 (8), 108 (99), 86 (26), 84 (39), 80 (56), 52 (19), 51 (26), 50 (7). HRMS (FAB) calcd for C9H10O2+H 151.0759, found 151.0760. Anal. Calcd for C9H10O2: C, 71.98; H, 6.71. Found: C, 71.55; H, 6.74; N, 0.19.

출처 및 근거

ORD 기록
ord-32384d7646b24fc29f067e1bb0caaed8
출처 데이터셋
uspto-grants-2006_01
특허 번호
US06992087B2

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