Chroman-4-one oxime → 2-ethyl-6-methoxy-2,3-dihydro-1H-inden-1-one oxime

반응식

O1C2C(=CC=CC=2)/C(=[N:11]/[OH:12])/CC1.[CH2:13]([CH:15]1[CH2:23][C:22]2[C:17](=[CH:18][C:19]([O:24][CH3:25])=[CH:20][CH:21]=2)[C:16]1=O)[CH3:14]>>[CH2:13]([CH:15]1[CH2:23][C:22]2[C:17](=[CH:18][C:19]([O:24][CH3:25])=[CH:20][CH:21]=2)[C:16]1=[N:11][OH:12])[CH3:14]

참가 물질

반응물 2

HCID 9673039Chroman-4-one oxime

HCID 218405792-Ethyl-6-methoxyindan-1-one

생성물 1

HCID 738670802-ethyl-6-methoxy-2,3-dihydro-1H-inden-1-one oxime

실험 절차

Following the procedure for the preparation of (4E)-2,3-dihydro-4H-chromen-4-one oxime but substituting 2-ethyl-6-methoxyindan-1-one and making non-critical variations provided the title compound as a oil: HRMS (FAB) calcd for C12H15NO2+H 206.1181, found 206.1175. Anal. Calcd for C12H15NO2: C, 70.22; H, 7.37; N, 6.82. Found: C, 69.90; H, 7.48; N, 6.64.

출처 및 근거

ORD 기록: ord-dfaf4f80f2ed45c7b020fe86e523e338
출처 데이터셋: uspto-grants-2006_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06992087B2

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