Methyl 3,5-dibromo-2-fluorobenzoate → Methyl 2-fluoro-3,5-bis-(2-oxopyrrolidin-1-yl)benzoate

HRID 1612450노트

반응식

HRID 1612450 반응식
[CH3:1][O:2][C:3](=[O:22])[C:4]1[CH:9]=[C:8]([N:10]2[CH2:14][CH2:13][CH2:12][C:11]2=[O:15])[CH:7]=[C:6]([N:16]2[CH2:20][CH2:19][CH2:18][C:17]2=[O:21])[CH:5]=1.BrC1C([F:35])=C(C=C(Br)C=1)C(OC)=O>>[F:35][C:5]1[C:6]([N:16]2[CH2:20][CH2:19][CH2:18][C:17]2=[O:21])=[CH:7][C:8]([N:10]2[CH2:14][CH2:13][CH2:12][C:11]2=[O:15])=[CH:9][C:4]=1[C:3]([O:2][CH3:1])=[O:22]

참가 물질

3

반응물 2

HCID 22252998Methyl 3,5-dibromo-2-fluorobenzoateHCID 693577583,5-Bis-(2-oxo-pyrrolidin-1-yl)benzoic Acid Methyl Ester

생성물 1

HCID 22253009Methyl 2-fluoro-3,5-bis-(2-oxopyrrolidin-1-yl)benzoate

실험 절차

Prepared in an analogous manner to D7 from methyl 3,5-dibromo-2-fluorobenzoate (D38).

출처 및 근거

ORD 기록
ord-3d631d6b6a2c4187bdceed69040a321d
출처 데이터셋
uspto-grants-2006_01
특허 번호
US06992103B2

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