Cyclopropanemethanol → Methyl 3-cyclopropylmethoxy-5-(2-oxopyrrolidin-1-yl)benzoate

반응식

[CH:1]1([CH2:4][OH:5])[CH2:3][CH2:2]1.O[C:7]1[CH:8]=[C:9]([CH:14]=[C:15]([N:17]2[CH2:21][CH2:20][CH2:19][C:18]2=[O:22])[CH:16]=1)[C:10]([O:12][CH3:13])=[O:11]>>[CH:1]1([CH2:4][O:5][C:7]2[CH:8]=[C:9]([CH:14]=[C:15]([N:17]3[CH2:21][CH2:20][CH2:19][C:18]3=[O:22])[CH:16]=2)[C:10]([O:12][CH3:13])=[O:11])[CH2:3][CH2:2]1

참가 물질

반응물 2

HCID 75644Cyclopropanemethanol

HCID 22252977Methyl 3-hydroxy-5-(2-oxopyrrolidin-1-yl)benzoate

생성물 1

HCID 22253024Methyl 3-cyclopropylmethoxy-5-(2-oxopyrrolidin-1-yl)benzoate

실험 절차

Prepared in an analogous manner to D14 (first part of synthesis) from cyclopropylmethanol and methyl 3-hydroxy-5-(2-oxopyrrolidin-1-yl)-benzoate (D41).

출처 및 근거

ORD 기록: ord-2471d78f68f64385b0294c1e48c4133f
출처 데이터셋: uspto-grants-2006_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06992103B2

반응 노트

불러오는 중…