Cyclobutanol → Methyl 3-cyclobutyloxy-5-(2-oxopyrrolidin-1-yl)benzoate

HRID 1612454노트

반응식

HRID 1612454 반응식
[CH:1]1([OH:5])[CH2:4][CH2:3][CH2:2]1.O[C:7]1[CH:8]=[C:9]([CH:14]=[C:15]([N:17]2[CH2:21][CH2:20][CH2:19][C:18]2=[O:22])[CH:16]=1)[C:10]([O:12][CH3:13])=[O:11]>>[CH:1]1([O:5][C:7]2[CH:8]=[C:9]([CH:14]=[C:15]([N:17]3[CH2:21][CH2:20][CH2:19][C:18]3=[O:22])[CH:16]=2)[C:10]([O:12][CH3:13])=[O:11])[CH2:4][CH2:3][CH2:2]1

참가 물질

3

반응물 2

HCID 76218CyclobutanolHCID 22252977Methyl 3-hydroxy-5-(2-oxopyrrolidin-1-yl)benzoate

생성물 1

HCID 22252979Methyl 3-cyclobutyloxy-5-(2-oxopyrrolidin-1-yl)benzoate

실험 절차

Prepared in an analogous manner to D14 (first part of synthesis) from cyclobutanol and methyl 3-hydroxy-5-(2-oxopyrrolidin-1-yl)-benzoate (D41).

출처 및 근거

ORD 기록
ord-807570546b5e42afa5808d78dc889e4e
출처 데이터셋
uspto-grants-2006_01
특허 번호
US06992103B2

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