Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Formaldehyde → 2-Tetradecynol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Formaldehyde | HCID 712 | — |
| 반응물 | 1-Tridecyne | HCID 117754 | — |
| 반응물 | Dodec-2-yn-1-ol | HCID 1712322 | — |
| 반응물 | Butyllithium | HCID 178418339 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 2-Tetradecynol | HCID 10965792 | — |
반응 단계
2-Tetradecyn-1-ol was prepared as described above for 2-dodecyn-1-ol except that 5.0 g (27 mmole) of 1-tridecyne in 200 ml of ether, 11.6 ml (29 mmole) of n-BuLi, and 874 mg (29 mmole) of paraformaldehyde was used. The reaction afforded a white solid after workup which was crystallized from petroleum ether to yield 4.78 g of white crystals, mp 44°-6° C. 1H NMR δ4.25 (m, 2), 2.20 (m, 2), 1.6-1.2 (m, 20), 0.88 (t, 3, J=7 Hz).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05190969 |
| 출처 데이터셋 | uspto-grants-1993_03 |
| ORD ID | ord-424fbd23b1ac45e19d8a9ca2fbc8cea8 |
| 출처 메모 | uspto-grants-1993_03 |