Thioacetamide → HCID 19775566, 화합물
반응식
Cl[CH:2]([C:13](=O)[CH2:14][CH2:15][CH3:16])[CH2:3][C:4]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][CH:5]=1.[C:18]([NH2:21])(=[S:20])[CH3:19]>C(OCC)(=O)C>[CH3:19][C:18]1[S:20][C:2]([CH2:3][C:4]2[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][CH:5]=2)=[C:13]([CH2:14][CH2:15][CH3:16])[N:21]=1참가 물질
4
실험 절차
A mixture of 5.9 of 2-chloro-1-(4-nitrophenyl)hexan-3-one and 1.7 g of thioacetamide is heated at 90°-100° C. for 6 hours and then cooled and taken up with ethyl acetate. The precipitate formed is filtered off and washed with ethyl acetate and then with ether to give 5.6 g of 2-methyl-4-propyl-5-(4-nitrobenzyl)thiazole in the form of crystals melting at 124° C.
후처리
- temperatureis heated at 90°-100° C. for 6 hours
- temperaturecooled
- customThe precipitate formed
- filtrationis filtered off
- washwashed with ethyl acetate
출처 및 근거
- ORD 기록
- ord-3e1147e8fe5b4d8db7257085361567d4
- 출처 데이터셋
- uspto-grants-1993_03
- 특허 번호
- US05192781
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