Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium hydride → Pentanobenzeneacetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | Benzocycloheptan-1-one | HCID 21703317 | — |
| 반응물 | 1-Ethoxycarbonylmethylbenzocycloheptane | HCID 53758794 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | Pentanobenzeneacetic acid | HCID 18918733 | — |
반응 단계
(Benzocyclohept-1-en-1-yl)-acetic acid was prepared from 1-ethoxycarbonylmethylbenzocyclohept-1-ene, which was itself prepared from benzocycloheptan-1-one treated with ##STR11## and NaH in tetrahydrofuran, followed by separation of the two exocyclic unsaturated cis- and trans-isomers also formed, the separation being carried out by flash chromatography on silica gel with toluene as eluant.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05194437 |
| 출처 데이터셋 | uspto-grants-1993_03 |
| ORD ID | ord-5c94360e4a7e40f3bb5d5ec38d85b435 |
| 출처 메모 | uspto-grants-1993_03 |