Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,6-Dichloropyrazine → 6-chloro-N-methyl-N-[(1S)-1-phenylethyl]pyrazin-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,6-Dichloropyrazine | HCID 78504 | — |
| 반응물 | (S)-(-)-N,alpha-Dimethylbenzylamine | HCID 2060073 | — |
| 생성물 | 6-chloro-N-methyl-N-[(1S)-1-phenylethyl]pyrazin-2-amine | HCID 58869921 | 39% |
반응 단계
In an analogous fashion to example 1, N-methyl-N-[(1S)-1-phenylethyl]amine (0.27 g, 2.0 mmol) was condensed with 2,6-dichloropyrazine (0.36 g, 2.4 mmol), to furnish the desired product as a light brown solid (192 mg, 39%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07737143B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-863f27e57344459eacf6de47048dfb92 |
| 출처 메모 | uspto-grants-2010_06 |