3-Bromoanisole → 3-(4-Phenyl-1H-imidazol-1-yl)phenol

반응식

[N:1]1([C:6]2[CH:7]=[C:8]([OH:12])[CH:9]=[CH:10][CH:11]=2)[CH:5]=[CH:4][N:3]=[CH:2]1.[C:13]1(C2N=CNC=2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.BrC1C=C(OC)C=CC=1>>[C:13]1([C:4]2[N:3]=[CH:2][N:1]([C:6]3[CH:7]=[C:8]([OH:12])[CH:9]=[CH:10][CH:11]=3)[CH:5]=2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

참가 물질

반응물 3

HCID 169713-Bromoanisole

HCID 104645913-(1H-Imidazol-1-yl)phenol

HCID 178418822HCID 178418822, 화합물

생성물 1

HCID 127184433-(4-Phenyl-1H-imidazol-1-yl)phenol수율 57%

실험 절차

Following the procedure for preparation of 3-(1H-imidazol-1-yl) phenol (preparation 29), 4-phenylimidazole (20 g, 0.138 mole) and 3-bromoanisole (32 ml, 0.25 mole) were reacted to give the title compound in 57% yield; mp 195°-197° C.

후처리

customwere reacted

출처 및 근거

ORD 기록: ord-54fc5832fd3444c396288c2ca22f39b8
출처 데이터셋: uspto-grants-1993_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05194446

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