2-Amino-4-methyl-thiazole-5-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide → 5-(3-Ethoxy-4-trifluoromethyl-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid [5-(2-hydroxy-1,1-dimethyl-ethylsulfamoyl)-4-methyl-thiazol-2-yl]-amide

반응식

[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6](-[c:14]2[n:15][c:16]3[n:17]([c:18]([C:20]([F:21])([F:22])[F:23])[cH:19]2)[n:24][cH:25][c:26]3[C:27](=[O:28])[OH:29])[cH:7][cH:8][c:9]1[C:10]([F:11])([F:12])[F:13].[OH:30][CH2:31][C:32]([CH3:33])([CH3:34])[NH:35][S:36](=[O:37])(=[O:38])[c:39]1[c:40]([CH3:45])[n:41][c:42]([NH2:44])[s:43]1>>[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6](-[c:14]2[n:15][c:16]3[n:17]([c:18]([C:20]([F:21])([F:22])[F:23])[cH:19]2)[n:24][cH:25][c:26]3[C:27](=[O:28])[NH:44][c:42]2[n:41][c:40]([CH3:45])[c:39]([S:36]([NH:35][C:32]([CH2:31][OH:30])([CH3:33])[CH3:34])(=[O:37])=[O:38])[s:43]2)[cH:7][cH:8][c:9]1[C:10]([F:11])([F:12])[F:13]