Chlorobenzene → Benzoic Acid

HRID 1613962

반응식

HRID 1613962 반응식
Cl[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C1(P(C(C(P(C2C=CC=CC=2)C2C=CC=CC=2)C)C)C2C=CC=CC=2)C=CC=CC=1.[C:38](=O)([O-:40])[O-:39].[K+].[K+].[C]=O>[Pd](Cl)Cl.O>[C:38]([OH:40])(=[O:39])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

7

반응물 4

HCID 7964ChlorobenzeneHCID 11430Potassium CarbonateHCID 3882352ChiraphosHCID 178418416HCID 178418416, 화합물2회

생성물 1

HCID 243Benzoic Acid

시약·촉매·용매 2

HCID 24290Palladium Chloride촉매HCID 962Water용매

반응 조건

온도
210 °C

실험 절차

In an autoclave made of metal were placed 11.2 g of chlorobenzene, 17.5 mg of palladium chloride, 427 mg of bisdiphenylphosphinobutane and 3.1 g of potassium carbonate. The air in the autoclave was replaced with carbon monoxide introduced thereinto in several times, after which carbon monoxide was further introduced to its pressure therein to 50 kg/cm2. The reaction was carried out with stirring for 3 hours on a salt bath at a bath temperature of 210° C. After completion of the reaction, the reaction mixture was cooled to room temperature and water was added. The aqueous layer was separated, after which acid was added thereto and the deposited crystals were collected by

후처리

  1. additionintroduced
  2. customAfter completion of the reaction
  3. temperaturethe reaction mixture was cooled to room temperature
  4. customThe aqueous layer was separated
  5. additionafter which acid was added
  6. customthe deposited crystals were collected by

출처 및 근거

ORD 기록
ord-095b683e6d924901b542fa981debd102
출처 데이터셋
uspto-grants-1993_03
특허 번호
US05194631

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