Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Quinolinic Acid → 2,3-Piperidinedicarboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Quinolinic Acid | HCID 1066 | — |
| 촉매 | Nickel aluminide | HCID 6336846 | — |
| 용매 | Sodium Hydroxide | HCID 14798 | — |
| 생성물 | 2,3-Piperidinedicarboxylic acid | HCID 1226 | — |
반응 단계
Dissolve pyridine-2,3-dicarboxylic acid (20 g, 120 mmol) in 0.5N aqueous sodium hydroxide (900 mL). Add nickel/aluminum powder (45 g) in portions over 3 hours. Stir for 4 days, filter off the catalyst to yield the title compound in clear solution. The resulting free amine is not isolated.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05194430 |
| 출처 데이터셋 | uspto-grants-1993_03 |
| ORD ID | ord-4ae1b8d90aed453fa680cafe417b52af |
| 출처 메모 | uspto-grants-1993_03 |