N-Methylbenzylamine hydrochloride → HCID 19773275, 화합물

반응식

[C:1]([NH:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][C:9](=O)[CH2:10]2)(=[O:3])[CH3:2].[ClH:16].[CH2:17]([NH:24][CH3:25])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[ClH:16].[C:1]([NH:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][CH:9]([N:24]([CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[CH3:25])[CH2:10]2)(=[O:3])[CH3:2]

참가 물질

반응물 2

HCID 9855548N-Methylbenzylamine hydrochloride

HCID 148364565-Acetylamino-2-tetralone

생성물 1

HCID 19773275HCID 19773275, 화합물

실험 절차

Starting from 2.03 g (0.01 mol) of 5-acetylamino-2-tetralone and 4.37 g (0.03 mol) of N-benzyl-methylaminehydrochloride the title compound is obtained analogously to Example 4.1.11 in a yield of 2.0 g (58.1% of theory) and with a melting point of 243° C. which does not change after recrystallisation from methanol/ether.

출처 및 근거

ORD 기록: ord-2350ae0a316c4ae9bff0be0cdf5ee138
출처 데이터셋: uspto-grants-1993_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05196454

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